Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. In addition, Fusion is pursuing combination programs between RCs and DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radiopharmaceutical manufacturing facility to meet supply demand for Fusion's growing pipeline of RCs.

Fusion is seeking outstanding applicants for a Research & Development Laboratory Manager to support a broad range of preclinical development activities. This position is lab-based, and located in Hamilton, Ontario, Canada.

Responsibilities (including, but not limited to):

• Oversight of the daily operations of the Biology, Imaging and Radiochemistry labs in the ILLF, as well as the Chemistry labs within Fusion’s R&D Facilities.
• Evaluate, organize, plan, direct, the maintenance needs of the Fusion Research labs, including: equipment maintenance and servicing, waste disposal, laboratory safety related inspections, laboratory cleaning services.
• Maintain external relationships with key consumable vendors, service providers (example: biohazard, chemical waste disposal, LN₂ supply and gas cylinder supply) and McMaster University CAF/AREB/Biosafety/Health Physics within the context and scope of enabling efficient operations of Fusions ILLF and animal facility.
• Support reagents and consumables ordering for the R&D Teams.
• Collaborate in cross-functional initiatives to help run the ILLF effectively and efficiently.
• Establish and maintain standardized processes, constantly review and implement new processes to drive continuous improvement in our operations.
• Participate in the implementation health and safety programs and activities such as training, communication, inspection, generation and review of safety SOPs and WIs, investigation and the promotion of general safety.
• Oversee and coordinate laboratory audits, safety compliance records, biological, chemical and radiological shipment/receiving paperwork, SDS/Biological, radiological and chemical inventories.
• Help coordinate shipments, deliveries and the scheduling of escorted maintenance personnel.
• Oversee daily delivery pick ups from main reception and the delivery to the appropriate lab/refrigerator/freezer or staff member.
• Escalate issues to upper management for support as required.
• Facilitate relationship building within the organization to improve lab initiatives.
• Manage a team of lab ops technicians who will support and execute on many of the above responsibilities.

Qualifications:

• Bachelor’s degree in Science, Health Sciences, Animal Sciences, Engineering, or a related field.
• 5-7 year of experience working with animals or in a clinical research lab environment.
• Organized with proven ability to work independently.
• Ability to work effectively in a multi-disciplinary team and communicate with colleagues at all levels.
• Experience with the safe handling of radioactive and biohazardous materials/waste.
• Willingness to take on new tasks and responsibilities as required.
• Ability to thrive in a fast-paced, dynamic environment and manage multiple priorities simultaneously.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.